Radiosensitization Effect Of Tantalum Nanoparticles Syntesized By Pulsed Laser Ablation Method In Deionized Water

Aji Pangestu, Ali Khumaeni, Eko Hidayanto

Abstract


This study explores the potential use of tantalum nanoparticles as radiosensitizing agents to improve the efficacy of radiotherapy in targeted tissues. The nanoparticles were synthesized using the pulsed laser ablation  technique in deionized water. Structural and morphological characterization was performed through Field Emission Scanning Electron Microscopy and X-ray Diffraction. To assess their radiosensitization capability, the degradation of methylene blue under exposure to X-rays and electron beams was analyzed. The results reveal that the synthesized tantalum nanoparticles are predominantly amorphous, with an average diameter of approximately 190 nm and a generally spherical shape. Furthermore, they demonstrated radiosensitizing effects, as indicated by a dose enhancement factor greater than one.

Keywords


Radiosensitizer; Nanoparticle; Tantalum; Laser Nd:YAG

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References


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DOI: http://dx.doi.org/10.52155/ijpsat.v50.1.7177

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